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ADVERTORIAL
                                                                                           World Liver Day




              Message from The Chairman                                    Non-Alcoholic Fatty liver disease

                                                            OMMONLY referred to as Fatty Liver dis-  sults of routine blood tests including  help improve the condition.  might suggest that you take Vitamin E. Vita-
                                                            ease,is a now a days a common in which  Liver Function tests and Scans (Ul-  Usually,you should lose weight if  min E can reduce some of the liver damage that
                                                        Cfat builds up in the liver.The liver is a big  trasound/Fibroscan test) of  you are overweight. It is impor-  occurs as part of NASH.You should avoid drink-
                                                        organ in the upper right side of the abdomen.  Liver        tant not to lose weight too  ing alcohol as it can worsen liver disease.
                                                          There are two types of fatty liver disease 1.  A liver biopsy is done to  quickly.Do not lose more than  Fatty Liver is typically a lifelong chronic con-
                                                        Nonalcoholic fatty liver-The liver has fat buildup  confirm fatty liver disease if  3.5 pounds (1.6 kilograms) a  dition.It is difficult to predict the course of Fatty
                                                        but is not inflamed. 2. Nonalcoholic steato-  other causes of liver disease  week. Treat your high blood  Liver.In some people Fatty Liver and sometimes
                                                        hepatitis (also called NASH) – In NASH,the liver  cannot be ruled out with  sugar, if you have high blood  it leads to serious scarring of the liver, called
                                                        has fat buildup and is inflamed.  standard imaging and blood  sugar and treat your high cho-  "cirrhosis." Cirrhosis can cause different symp-
                                                          People who drink too much alcohol can get a  tests.      lesterol, if you have high choles-  toms, such as swelling in the legs, trouble
                                                        condition similar to Non-alcoholic fatty Liver                terol. These changes can  breathing,or feeling tired.
                                                        disease,but non-alcoholic fatty Liver disease is  TREATMENT   also reduce your chances  Therefore,people who have Fatty Liver need
                                                        not related to drinking too much alcohol.  Fatty Liver is not typically  Dr.Amit Bhasin, MBBS,MD,DM,  of having a heart attack or  to see their doctor for regular check-ups.
                                                          Fatty Liver happens more often in some peo-  treated directly. But the  Sr.Consultant,Gastroenterology   stroke. That is important  Your doctor will do follow-up tests on a regu-
                                                        ple are overweight, have diabetes, have high  condition can get better  & Hepatology  because people with Fatty  lar basis like blood tests and Scans of Liver.
                                                        cholesterol,take certain medicines  when other medical condi-  Liver are often also at risk  The usual Mantras for fatty liver are,follow a
                                                          Most people with fatty Liver have no symp-  tions that often happen with fatty Liver get  for heart disease and stroke.  healthy lifestyle, avoid alcohol, control for dia-
               “WITH The divine blessings of Lord       toms.                     treated. For example, losing weight, and con-  If you have a severe form of NASH but do not  betes and cholesterol and maintain a healthy
               Venkateshwara, we dedicate and strengthen our  Fatty Liver is usually diagnosed from the re-  trolling high blood sugar and cholesterol can  also have diabetes or heart disease,your doctor  weight.
               services to the society by transforming our
               humble efforts from education to health care. The  Keeping the Liver Safe From Tumors and Cancer
               Objective of the Venkateshwar Hospital  would be
               to provide solace to the suffering humanity with  Dr Amardeep Yadav, a Senior Con-  overall prognosis of patients   transplant later. Transplantation is an ag-
               a healing, soothing and humane touch.”        sultant, Liver Transplant, GI Surgery & GI  with HCC even in advance  What all surgeries are  gressive treatment, but oncologically a
                                                             Oncology at Venkateshwar Hospital, Delhi  stages.Unfortunately,most  done for liver cancer?  more superior procedure that takes care of
               Mr. Rajpal                                    on the World Liver Day shares some impor-  of these patients are ei-  Liver  cancer  requires  the diseased liver also.5-year survival rate
                                                             tant fact about liver tumours and cancers  ther referred late by pri-  surgery where all the tu-  after transplant for HCC are 70-80% and if
                                                             with advise for early detection and treat-  mary care physicians or  morous part is removed  size of tumor is less then 5cm then it can
                                                             ment for best results.  avoid due to fear of            leaving behind at-least  reach upto 90%.
               World Liver Day: Liver it up!                                        surgery. It must be em-         30% of normal liver with
                                                             What are the types of liver cancer  phasized that if proper  blood supply and biliary  What are the contraindications for
                                  disease (cirrhosis) results - liver  and the conditions predisposing a  treatment is done on time,  drainage. This is called liver  transplant in liver and bile duct can-
                                  can’t fulfil body requirements. Pa-  person to develop them?  then a cure rate of 70-  resection which can be  cers?
                                  tients with cirrhosis are prone to  Primary liver cancer that originates from  80% can be achieved,  Dr Amardeep Yadav  done if the liver is nor-  Liver transplant cannot be done in termi-
                                  develop liver cancer, others grad-  liver cells (hepatocytes) is known as He-  which is highest in any  Senior Consultant,Liver Transplant,  mal and tumors are in  nally ill patient and strictly avoided if the
                                  ually deteriorate. Symptoms com-  patic Cell Carcinoma (HCC) and from bile  solid organ cancer till  GI Surgery& GI Oncology  favorable location.But  cancer spreads out of the liver. Portal vein
                                  pel patients with cirrhosis to seek  duct system called colangiocarcinomas. If  now.  resection has higher  tumor thrombus, a condition where tumor
                                  medical attention and complica-  cancer spreads to the liver from other or-         recurrence rate which  spreads into the blood vessels of liver
                                  tions develop which necessitate  gans like breast,lungs,colon etc.,it is called  What are the treatment options for  can be upto 50-60%. In damaged liver (cir-  which can be picked up on CT scan or ultra-
                                  admission to hospital.Each hospi-  secondary liver cancer.Anyone with family  liver cancers/ HCC?  rhotic liver) and multiple cancers in all of  sound is a relative contraindication as
                                  talisation puts patient at risk of  history of liver cancer,aged above 20 years,  Treatment of liver cancer depends on the  the liver,resection is usually not possible as  some of these patients can be transplanted
                                  death and increases treatment  certain ethnic origin,people suffering from  stage of liver cancer depending on the size  the cancerous liver has to be removed re-  after special procedures giving radiother-
                                  costs. At this stage of recurrent  liver cirrhosis, especially due to alcohol,  of tumor,number of liver tumors and if one  placing it with normal liver. This is called  apy by EBRT (External Beam Radio Therapy)
                  Dr K R Vasudevan  episodes of decompensation or  NAAFLD, hepatitis B, hepatitis C infection  or both lobes of liver and condition of rest of  liver transplant, where recurrence rate is  or TARE with Itrium90(Trans Arterial Radio
               Director GI Surgery,GI Oncology &  development of liver cancer, the  have high risk of developing HCC. These  the liver. If any other structure in addition to  less and survival chances better.If resection  Embolization).
                    Liver Transplant
                                  disease can’t be cured with med-  people should be screened periodically  liver are involved like blood vessels or  can be done safely,it is the best option as it  For bile duct cancers /colangiocarcino-
                                  ication and most patients suc-  with blood AFP levels and ultrasound of  neighboring organs then treatment plan-  is relatively less aggressive surgery,cost ef-  mas, liver resection involving removal of
               Dr K R Vasudevan, Director GI  cumb to the disease in a few  liver. If in doubt, they should undergo CT  ning has to be done looking at overall pic-  fective and life-long immunosuppressant  the cancerous part with the adjoining liver
               Surgery,GI Oncology & Liver  months despite repeated visits  triphasic scan of liver.  ture.If cancer is picked up at an early stage  are not required. If recurrence of tumour  gives the best results. Patients are mostly
               Transplant draws the attention to  and admissions to hospital. The   <2 cm size, then it can be managed with  happens then a salvage transplant at a  treated for liver infection(cholangitis) with
               ‘World Liver Day’ which is ob-  best treatment for patients in this  How is prognosis expected for liver  non-surgical measures like RFA,TACE,TARE  later stage can be done in 30-40% of these  antibiotics,draining the obstructed bile sys-
               served on 19 April with focus on  stage is to replace the liver with a  tumors?  etc. After these procedures, follow up for  patients.  tem, assessment of volumes of liver to be
               the liver - an organ vital to our  new one - liver transplantation.  Progress in treatment protocols, diagnosis  new tumor or same tumor growing back is  More than half of resection happen out-  removed and remaining liver after surgery
               well-being. In fact, without the              and timely intervention has improved the  important.  side the liver making them unsuitable for  to prevent liver failure post-surgery.
               liver, one can survive only for a  Liver transplantation, how
               couple of days. But fortunately,  effective is this procedure?
               the liver is a benevolent organ and  Results of liver transplantation are  Crusader against Alcoholism for Liver Longevity
               can be kept healthy by practising  good, majority of them will go on
               (common) measures to keep body  to live normal lives for many years -
               healthy. Let us get to know more  some of these patients are surviv-  On the occasion of World Liver Day,  for 50% of mortality related to liver  transplant only after abstaining from  one must not go beyond it. Upto 10 gms of al-
               from him.          ing over 40 years after transplan-  Dr Rohit Goyal, who is passionate about  cirrhosis. In India, alcohol is the  alcohol for a period of atleast 6  cohol in a week for women and upto 20 gms
                                  tation.These patients regain their  eradicating alcoholism for a healthy liver, has  underlying cause in 34% of all  months. But now early trans-  for men is supposed to be safe. Liver damage
               What leads to liver being dis-  full vitality, are able to perform  stepped up awareness to blunt the menace.  liver cirrhosis cases and more  plant can also be considered  usually occurs with weekly alcohol intake of
               eased and how can it be  their duties and accomplish their  He has packed extensive experience within a  than 50% of patients with  after appropriate counselling  > 30 gms for women and > 50 gms for men
               managed?           desires - like return to full time  span of 13 years in various liver related inter-  other liver disease also con-  if patient is critically sick.  for more than 5 years. Generally, people do not
               Liver damage occurs slowly, over  work,(including the army) and per-  ventions as Senior Consultant, Gastroenterol-  sume significant alcohol.  adhere to the limits and that is the root of the
               years, usually gives us indication  form all activities like climbing  ogy and Hepatology, in Delhi’s premier hospi-  About 90% of heavy drinkers  What are the symptoms  problem.
               and time to investigate and course  snow clad mountains and play all  tals Max Superspeciality Hospital, Patparganj  develop fatty liver and 10%  of a sick liver when alco-
               correct.We may be unaware of on-  sports.This is not possible without a  and BLK Superspeciality, Rajendra Place. He  develop liver cirrhosis. Patient  hol abuse is excessive?  What are the reasons for increased alco-
               going damage like in viral infec-  transplant operation.  shares his views on the subject.  with liver cirrhosis have  The most common symp-  hol intake by people despite evident
               tions - hepatitis, or some genetic                                 progressive risk of devel-  Dr Rohit Goyal  toms include jaundice, fa-  harmful effects?
               abnormalities where we can’t help  Could you share about liver  What are the kinds of liver diseases  oping liver failure and  Senior Consultant,Gastroenterology  tigue, loss of body mass  Overall, per capita alcohol consumption
               prevent the damage till symptoms  treatment at Venkateshwar  prevalent in the world, and particularly  liver cancer, which is  and Hepatology  and a pale look. If liver cir-  worldwide has increased with people starting
               (problems) appear.Often it is from  Hospital?  in India?           about 1 percent in a year.          rhosis sets in, patient may  to take alcohol at a much younger age. Also,
               reasons we know - alcohol intake  Liver transplantation started in In-  The major causes of liver diseases worldwide  develop accumulation of  proportion of women with alcohol related liver
               and fatty liver, and it is upto us to  dia on a large scale in the 2000’s,  and in India are similar. In India, the common-  Liver is regenerative, so how does that  fluid in the belly, drowsiness and memory loss  diseases is rising. In India, lifestyle have
               limit further damage. Either way,  we now perform one of the largest  est causes for liver diseases are alcohol (ALD);  help in managing diseases related to it?  or the vomiting of blood through the mouth  changed drastically. Professional related
               the liver gives us time… If we are  number of transplants in the  obesity and diabetes related fatty liver (Non-al-  The good thing about liver being a regenerative  or the stool, and internal bleeding may hap-  stress, increased purchasing power, easy avail-
               able to prevent further damage,  world. At Venkateshwar Hospital,  coholic Fatty Liver Disease or NAFLD) and He-  organ is that if the person is detected early for  pen. Other internal organs like heart and  ability of alcohol and peer pressures are con-
               the liver recovers completely, es-  we have an experienced team  patitis B and C viruses. The proportion varies  ALD and is counselled to abstain from it, then  nerves can also be damaged by alcohol leading  tributing to rising alcohol consumption. Recre-
               pecially if action is taken early.  which has been performing trans-  in different parts of the country e.g., Hepatitis  the early part of the disease can be reversed  to heart failure, burning sensation, numbness  ational use of alcohol and drugs is rising, and
                                  plants for the last 2 years,both live  C is most common in the north, NAFLD is more  and the liver can go back to normal. In ad-  and weakness of limbs.  its addiction difficult to break. Lack of aware-
               How fatal is liver cirrhosis?  related and deceased donor trans-  pronounced in the west, while alcohol and He-  vanced stages of liver cirrhosis, transplant may  ness about harmful effects of alcohol in middle
               If not controlled, end stage liver  plants,on adults and children.  patitis B are most prevalent in the east, North-  be the only treatment option. Previously, pa-  What is the safe limit of alcohol intake?  and lower economic sections may also con-
                                                        east and south. Worldwide, alcohol accounts  tient having liver cirrhosis could undergo liver  Alcohol intake limits are clearly defined and  tribute to the menace.
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