{"id":91,"date":"2018-08-13T09:47:38","date_gmt":"2018-08-13T09:47:38","guid":{"rendered":"https:\/\/www.venkateshwarhospitals.com\/blog\/?p=91"},"modified":"2018-09-24T11:54:06","modified_gmt":"2018-09-24T11:54:06","slug":"liver-transplantation-a-second-innings-to-life","status":"publish","type":"post","link":"https:\/\/www.venkateshwarhospitals.com\/blog\/liver-transplantation-a-second-innings-to-life\/","title":{"rendered":"Liver Transplantation \u2014 A Second Innings To Life"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-114 size-full\" src=\"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-content\/uploads\/2018\/08\/Dr-Anupam-Saha.jpg\" alt=\"Dr Anupam Saha\" width=\"1500\" height=\"2100\" srcset=\"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-content\/uploads\/2018\/08\/Dr-Anupam-Saha.jpg 1500w, https:\/\/www.venkateshwarhospitals.com\/blog\/wp-content\/uploads\/2018\/08\/Dr-Anupam-Saha-214x300.jpg 214w, https:\/\/www.venkateshwarhospitals.com\/blog\/wp-content\/uploads\/2018\/08\/Dr-Anupam-Saha-768x1075.jpg 768w, https:\/\/www.venkateshwarhospitals.com\/blog\/wp-content\/uploads\/2018\/08\/Dr-Anupam-Saha-731x1024.jpg 731w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/><\/p>\n<p style=\"text-align: justify;\">Liver transplantation is the only life-saving procedure available for patients with chronic end stage liver diseases and selected patients with acute liver failure. The survival following liver transplant for an otherwise fatal condition is about 86% at 1 year, 72% at 5 years and 50% at 20 years. Liver donation for transplantation can be obtained either from deceased donors or living donors. Deceased donors are individuals who suffer Brain Stem Death following severe head injury or brain stroke. Organs are retrieved once consent is given by the next of kin. Living donor liver transplantation (LDLT) was introduced because of the increasing demand for donor organs and the widening gap between the resource (deceased donor) and the demand (recipient).<\/p>\n<p style=\"text-align: justify;\"><strong>THE PROCEDURE Selection of liver donors <\/strong><\/p>\n<p style=\"text-align: justify;\">\u25a0 Only blood group matching requires to be done to select the recipient.<\/p>\n<p style=\"text-align: justify;\">\u25a0 Donors with blood type A can donate to recipients with blood types A and AB<\/p>\n<p style=\"text-align: justify;\">\u25a0 Donors with blood type B can donate to recipients with blood types B and AB<\/p>\n<p style=\"text-align: justify;\">\u25a0 Donors with blood type AB can donate to recipients with blood type AB only<\/p>\n<p style=\"text-align: justify;\">\u25a0 Donors with blood type O can donate to recipients with blood type A, B,AB and O (O is the universal donor and are compatible with any other blood type)<\/p>\n<p style=\"text-align: justify;\">\u25a0 There is no age limit for organ donation. Usually the whole deceased donor liver is transplanted. However, the whole liver can be split into two to transplant an adult as well as a child.<\/p>\n<p style=\"text-align: justify;\">\u25a0 In most transplant centres, age limit for liver donation is 18-55 years.<\/p>\n<p style=\"text-align: justify;\">\u25a0 Volume of liver required \u2014 A liver recipient requires the donor liver to be at least 0.8% of the body weight.<\/p>\n<p style=\"text-align: justify;\"><strong>Organ Retrieval <\/strong><\/p>\n<p style=\"text-align: justify;\">\u25a0 Deceased donor \u2014 Liver is usually retrieved as part of a multi organ donor retrieval and is a surgical procedure.<\/p>\n<p style=\"text-align: justify;\">\u25a0 Living donor \u2014 The surgical procedure involves removal of either the right side of the liver for transplanting into an adult or a small portion of the left side for a child. A liver donor can donate up to 65% of the whole liver.<\/p>\n<p style=\"text-align: justify;\"><strong>Organ Preservation<\/strong><\/p>\n<p style=\"text-align: justify;\">This involves preserving the liver for a short time in cold preservative solution. It can be preserved for not more than 12-14 hours.<\/p>\n<p style=\"text-align: justify;\"><strong>Transplantation Recipient Hepatectomy <\/strong><\/p>\n<p style=\"text-align: justify;\">The diseased liver is removed from the recipient. This is often a difficult part of the transplant process.<\/p>\n<p style=\"text-align: justify;\"><strong>Liver graft implantation<\/strong><\/p>\n<p style=\"text-align: justify;\">The donor liver is implanted by joining the multiple blood vessels of the donor liver with those in the recipient followed by joining of bile ducts.<\/p>\n<p style=\"text-align: justify;\"><strong>Post Transplant Care Immunosuppression<\/strong><\/p>\n<p style=\"text-align: justify;\">Immunosuppression is of paramount importance to prevent rejection of the transplanted liver and is to be continued lifelong. It needs to be monitored and a fine balance needs to be maintained to reduce the risks of infection and side effects.<\/p>\n<p style=\"text-align: justify;\"><strong>Written By: Dr. (Brig) Anupam Saha (Venkateshwar Hospital)<\/strong><\/p>\n<p style=\"text-align: justify;\">MBBS, MS (Gen Surg),<\/p>\n<p style=\"text-align: justify;\">Fellowship GI Surgery (AIIMS, New Delhi) and Liver Transplantation (KCH London) Senior Consultant &amp; HOD<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Liver transplantation is the only life-saving procedure available for patients with chronic end stage liver diseases and selected patients with acute liver failure. The survival following liver transplant for an otherwise fatal condition is about 86% at 1 year, 72% at 5 years and 50% at 20 years. Liver donation for transplantation can be obtained&#8230;<\/p>\n","protected":false},"author":1,"featured_media":92,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[15,14],"class_list":["post-91","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-liver-transplant","tag-liver-transplant","tag-liver-transplantation"],"_links":{"self":[{"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/posts\/91","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/comments?post=91"}],"version-history":[{"count":2,"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/posts\/91\/revisions"}],"predecessor-version":[{"id":115,"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/posts\/91\/revisions\/115"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/media\/92"}],"wp:attachment":[{"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/media?parent=91"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/categories?post=91"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.venkateshwarhospitals.com\/blog\/wp-json\/wp\/v2\/tags?post=91"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}